5 Simple Statements About valium sverige Explained
5 Simple Statements About valium sverige Explained
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metronidazole will boost the degree or outcome of diazepam by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Check.
The anticonvulsant properties of diazepam and other benzodiazepines could be partially or completely because of binding to voltage-dependent sodium channels in lieu of GABAA receptors.
stiripentol will minimize the level or influence of diazepam by affecting hepatic enzyme CYP2C19 metabolism. Modify Therapy/Keep an eye on Carefully. Take into consideration decreasing the dose of CYP2C19 substrates, if adverse reactions are professional when administered concomitantly with stiripentol.
地西泮在口服後，迅速被身體吸收，藥效很快開始，以靜脈注射，藥效更快。地西泮經肝臟代謝，其代謝物經腎臟排泄，只有極少量的地西泮沒有被代謝便排泄。
cyclophosphamide will raise the degree or impact of diazepam by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Small/Importance Mysterious.
Paradoxical reactions may well come about which include hallucinations, intense habits, and psychoses; dinscontinue use if reactions take place
Reserve concomitant prescribing of those medication in sufferers for whom other procedure solutions are inadequate. Limit dosages and durations to the bare minimum needed. Observe intently for indications of respiratory despair and sedation.
As a consequence of isolated reviews of neutropenia and jaundice, periodic blood counts and liver functionality checks are recommended through very long-phrase therapy
Even though significantly less popular, by far the most severe side effects of diazepam are explained below, along with how to proceed should they materialize.
crofelemer increases amounts of diazepam by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Watch. Crofelemer has the probable to inhibit CYP3A4 at concentrations envisioned from the intestine; unlikely to inhibit systemically simply because minimally absorbed.
Coadministration of other CNS depressants or Alcoholic beverages usage could potentiate CNS-depressant results of diazepam
triclabendazole will improve the stage or more info influence of diazepam by affecting hepatic enzyme CYP2C19 metabolism.
Diazepam does not boost or decrease hepatic enzyme activity and would not alter the metabolism of other compounds. No evidence has recommended that diazepam alters its metabolism with Serious administration.[29]
常见：嗜睡、头晕、乏力，大剂量可有共济失调、震颤、顺行性遗忘、认知损害。